The goal of SAPESUCA is to provide some essential functions to calculate the peritoneal surface area (PSA) individually for each patient. After calculating the global PSA, we are able to assess the quantitative PSA before and after cytoredution (surgery). The underlying idea is to provide a reproducible and comparable definition of the resected PSA across different institutions. The next step is to calculate the dosage of the chemotherapy during hyperthermic intraperitoneal chemotherapy (HIPEC) adapted to the remaining PSA.This is already integrated to SAPESUCA and must be proofed in clinical studies.
Installation
You can install the development version of SAPESUCA from GitHub with:
# install.packages("devtools")
devtools::install_github("TarJae/SAPESUCA")Code of Conduct
Please note that the SAPESUCA project is released with a Contributor Code of Conduct. By contributing to this project, you agree to abide by its terms.
Working app
You can try the working app SAPESUCA here
How to use the app
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On the rightsidebar go to BSA tab and fill in the patient ID, the date of HIPEC, the height and the weight of the patient. Now the body surface are is calculated with the Dubois formula:
Surface(m^2) = 0.20247 * height (m)^{0.725} * weight (kg)^{0.425}
In the CRS tab first select the anatomical region (region 0 to 12). Then use the slider to indicate the resected peritoneal area of that specific region (e.g. Transverse colon. Note there are also separate regions for the transverse mesocolic regions).
Finally in the HIPEC tab provide the used chemotherapy with its dose (mg/² BSA).
You will notice the simultaneously calculation of the peritoneal surface aree (PSA) before and after cytoreduction. Note: The concordance between the peritoneal surface area (PSA) and body surface area are generally accepted in clinical practice and underpinned by the study of Albanese et al. in 2009. Simultaneously, in the background, the chemotherapy dosage is calculated to be adjusted to the peritoneal surface are using an algorithm published in our paper (xxx).
The results can be obtained either in form of a radar chart or as a table to download and save. There is also the possibility to print a report.
